Jun-Yang Liou 劉俊揚 研究員
Our research interests focus on three areas. The first is investigating the potential signal and molecular regulation that modulates vascular inflammation, artery stenosis and myocardial injury. The second is the establishment of human-induced pluripotent stem cells (iPSCs) and its differentiation into cardiovascular-related cells. We have thoroughly established the optimal protocol for differentiation of human iPSC-derived cardiomyocytes (iPSC-CMs), which can then be applied to drug screening of cardiotoxicity for early drug safety de-risking, and additionally reducing the amounts of experimental animals sacrificed. Finally, we have discovered several signal regulators that are involved in the triggering of tumor progression in hepatocellular carcinoma. The achieved applications have been assessed by multiple strategies, including in vitro analysis of cellular function, as well as in vivo animal study and validation in human clinical samples.
EDUCATION / 學歷
1992 – 1996 |
Ph.D., Plant Pathology and Entomology, National Taiwan University, Taipei, Taiwan |
1987 – 1991 |
B.S., Plant Pathology and Entomology, National Taiwan University, Taipei, Taiwan |
EXPERIENCE / 經歷
2020/07 – present |
Investigator, Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan |
2022/09 – present |
Director, Department of Research Planning and Development, National Health Research Institutes, Zhunan, Taiwan |
2020/01 – 2022/08 |
Deputy Director, Department of Research Planning and Development, National Health Research Institutes, Zhunan, Taiwan |
2019/08 – 2020/07 |
Acting Deputy Director, Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan |
2019/03 – 2020/02 |
Chief, the Student Affairs Office, National Health Research Institutes, Zhunan, Taiwan |
2014/01 – 2015/06 |
Chief, the Student Affairs Office, National Health Research Institutes, Zhunan, Taiwan |
2010/10 – 2020/06 |
Associate Investigator, Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan |
2008 – 2010 |
Assistant Investigator, Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan |
2007 – 2008 |
Assistant Investigator, Cardiovascular and Blood Medical Research Center, National Health Research Institutes, Zhunan, Taiwan |
2005 – 2007 |
Assistant Professor, Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA |
2004 – 2005 |
Instructor, Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA |
2002 – 2004 |
Senior Research Fellow, Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA |
2000 – 2002 |
Postdoctoral Fellow, Institute of Biological Sciences, Academia Sinica, Taipei, Taiwan |
1999 – 2000 |
Research Fellow, Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA |
1998 – 1999 |
Postdoctoral Fellow, Institute of Biological Sciences, Academia Sinica, Taipei, Taiwan |
LAB MEMBER / 研究團隊
PUBLICATIONS / 論文著作
PubMed Search
NHRI Institutional Repository國家衛生研究院機構典藏