Our research centers around finding easily accessible sources of human mesenchymal stem cells (MSCs)—including from ethically compliant term placenta and pluripotent stem cells, including human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs)—for therapeutic application. MSCs are multipotent somatic stem/progenitor cells with immunomodulatory properties towards diverse leukocyte populations. The strong immunomodulation of MSCs allow for use of these versatile progenitors in regenerative medicine as well as immune/inflammatory diseases. Moreover, these properties also allow for unmatched allogeneic use, thereby expanding the clinical use of MSCs as readily available, “off-the-shelf” products. Our lab has special interest in elucidating the molecular mechanisms involved in tissue-specific MSC immunomodulation, as well as MSC tissue engineering for regenerative medicine, including for angiogenesis and generation of artificial blood vessels in line with ICSM/institute mission-oriented goals.
EDUCATION / 學歷
| 1991 – 1996 | M.D., School of Medicine, University of California at San Francisco (UCSF), CA, USA |
| 1986 – 1991 | B.A., Summa Cum Laude, Music (Specializations: History/Literature & Performance), School of Fine Arts, University of California at Los Angeles (UCLA), CA, USA |
EXPERIENCE / 經歷
| 2017/09 – present | Deputy Director, Institute of Cellular & System Medicine (ICSM), National Health Research Institutes (NHRI), Zhunan, Taiwan |
| 2014/07 – present | Investigator & Attending Physician, Regenerative Medicine Research Group (RMRG; formerly Stem Cell Research Center), ICSM, NHRI, Zhunan, Taiwan |
| 2009 – 2014 | Associate Investigator & Attending Physician, RMRG, ICSM, NHRI, Zhunan, Taiwan |
| 2005 – 2009 | Assistant Investigator, & Attending Physician, RMRG, ICSM, NHRI, Zhunan, Taiwan |
| 2003/03 | Visiting scientist, Human Embryonic Stem Cell (hESC) Research Center, UCSF, San Francisco, CA, USA |
| 2003/10 | hESC research trainee, ES Cell International Inc., Melbourne, Australia |
| 2002 – 2005 | Postdoctoral Fellow, Stem Cell Research Center, NHRI, Zhunan, Taiwan |
| 1998 – 2001 | Resident: Post-Graduate Year 2 (PGY2), PGY3 & Chief Resident, Dept. of Obstetrics/Gynecology, National Taiwan University-Hospital-En Chu Kong Hospital Joint Program, Taipei, Taiwan |
| 1996 – 1997 | Resident: PGY1, Dept. of Obstetrics/Gynecology, UCLA Medical Center, Los Angeles, CA, USA |
| 1993 – 1994 | Post-Sophomore Fellow, Dept. of Pathology, UCLA Medical Center, Los Angeles, CA, USA |
LAB MEMBER / 研究團隊
| 姓名 | 職稱 | 分機 | |
|---|---|---|---|
| 謝承展 | 博士後研究員 | 37518 | 120320@nhri.edu.tw |
| 徐珮茹 | 研究助理 | 37518 | 971108@nhri.edu.tw |
| 廖倩玉 | 研究助理 | 37518 | chiann@nhri.edu.tw |
| 王修洹 | 研究助理 | (02)27929655 | 030832@nhri.edu.tw |
| 馮千庭 | 研究助理 | 37518 | Diabolo@nhri.edu.tw |
| 張家齊 | 國防大學博班生 | 37518 | 084052@nhri.edu.tw |
HONOR & AWARDS/ 榮譽獎項
| 2015 | Outstanding Research Achievement Award, NHRI/國衛院 傑出學術成就獎 |
| 2013 | 10th National Innovation Award—Academic Research Category, Institute for Biotechnology & Medicine Industry (IBMI), Taiwan/財團法人國家生技醫療產業策進會 (生策會) 第十屆國家新創獎/學研組 |
| 2010 | Junior Researcher Award, Academia Sinica, Taiwan/中央研究院 年輕學者研究著作獎 |
| 2010 | Young Scientist Award, NHRI/國衛院 年輕學者學術成就獎 |
| 2009 | Ta-you Wu Young Scientist Award, Ministry of Science & Technology (MoST), Taiwan/科技部 吳大猷先生紀念獎 |
| 1997 | Best Resident Award, Dept. of Obstetrics/Gynecology, UCLA Medical Center/ UCLA醫學中心 婦產科 最佳住院醫師獎 |
| 1996 | Exchange Student Scholarship, UCSF/Peking Union Medical College/ UCSF/北京協和醫院交換醫學生獎學金 |
| 1992 | Exchange Student Scholarship, UCSF/University of Heidelberg/ UCSF/德國海德堡大學交換研究生獎學金 |
| 1991 | Outstanding Graduating College Senior Award, UCLA Alumni Association/UCLA傑出大學畢業生獎 |
| 1991 | Chancellor’s Service Award, UCLA/ UCLA校長服務獎 |
| 1991 | Induction into Phi Beta Kappa National Honor Society/獲選加入美國Phi Beta Kappa之榮譽學會 |
| 1990 | Induction into Mortar Board (UCLA College Senior Honor Society) |
| 1989 | Distinguished Scholar Award, UCLA Alumni Association/ UCLA 傑出大學學者獎 |
PUBLICATIONS / 論文著作
NHRI Institutional Repository國家衛生研究院機構典藏
